E.U. May ‘Unravel’ if U.K. Quits, Official Says







LONDON — Almost 40 years after Britain joined the forerunner of today’s European Union, the debate over the country’s future in the Union has quickened with a warning from a top E.U. official that any moves to renegotiate the terms of British membership could wreck the bloc.




Herman Van Rompuy, president of the European Council, the body that groups the 27 E.U. member states, said that the European Union had benefited tremendously from British membership and that Britain’s departure would be like seeing “a friend walk off into the desert.”


But Mr. Van Rompuy also suggested that the strategy developed by Prime Minister David Cameron to restore dwindling public support for keeping Britain inside the bloc was likely to fail.


In an interview published Friday in The Guardian, a British daily, Mr. Van Rompuy said that renegotiation could undermine the one part of the European Union that Mr. Cameron says he values most: the single market under which around 500 million Europeans can do business without barriers.


“If every member state were able to cherry-pick those parts of existing policies that they most like, and opt out of those that they least like, the Union in general, and the single market in particular, would soon unravel,” he said.


The intervention from Mr. Van Rompuy highlights the fact that other nations are likely to resent a process under which Britain seeks to retain the parts of E.U. membership that it likes, while rejecting the rest. In order to renegotiate British membership terms, all other member states would have to agree on the changes.


And, if that sort of discussion begins, other countries may make demands too, including some that could weaken the single market which seeks to establish a level playing field on trading issues.


“All member states can, and do, have particular requests and needs that are always taken into consideration as part of our deliberations,” Mr. Van Rompuy said in the interview. “I do not expect any member state to seek to undermine the fundamentals of our cooperative system in Europe.”


Mr. Cameron argues that, to persuade euro-skeptical British voters to stay in the European Union, the country should loosen its political and social policy ties to the Union and refocus them around Europe’s single economic market. He wants to renegotiate the terms of British membership and seek approval for the result of that negotiation from the public, possibly in a referendum.


Britain formally joined in the process of European integration in 1973, when it acceded to the European Economic Community. Two years later, after a change of government and negotiations on the terms of membership, it held a referendum in which around two-thirds of those who voted elected to stay.


One theory in Britain is that the euro debt crisis presents a new opportunity to re-fashion the process of European integration because the 17 countries that use the single currency may need to rewrite the Union’s governing treaties in order to become more closely integrated. That could give Britain the chance to negotiate its looser relationship simultaneously as part of a grand bargain.


Mr. Van Rompuy suggested, however, that such a rewriting of the treaties might not happen because it might not be necessary.


“The treaties allow a considerable degree of flexibility and much can be done without needing to amend them,” he told The Guardian. “It is perfectly possible to write all kinds of provisions into the treaties, but amending them is a lengthy and cumbersome procedure needing the unanimous agreement of every single member government and ratification.”


Mr. Van Rompuy’s comments come at a sensitive moment, ahead of a widely anticipated speech by Mr. Cameron, expected in mid-January, during which he might make the promise of a referendum explicit. Many of his own lawmakers now want Mr. Cameron to promise a straight “in or out” vote, though he has so far resisted.


The political mood within Mr. Cameron’s Conservative Party has hardened against engagement with Europe, partly because of the rise in popular support for the U.K. Independence Party, which has campaigned for Britain to leave the European Union and for tighter immigration controls.


UKIP is expected to do well in the next elections to the European Parliament in 2014, which will be held under a proportional electoral system that favors smaller parties. The party is unlikely to win many, or even any, seats in British parliamentary elections, expected the following year, because these will be fought under a first-past-the post system that tends to favor mainstream parties.


The smaller party could, though, take enough votes from the Conservative Party to deprive it of the seats it will need to form the next government.


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The Boy Genius Report: The Wii U is the Nintendo’s last console






I remember it still — people flipped out about the Nintendo (NTDOY) Wii. Yes, its name was mocked for a while, but there was genuine excitement around what Nintendo was doing with motion and the entire gameplay experience. While the original Nintendo Wii was almost an Apple (AAPL)-like product — Nintendo focused on the gameplay and not on specs; the company didn’t even have HD graphics when every other console did — the Nintendo Wii U clearly demonstrates how far Nintendo has fallen and how out of touch the company is.


[More from BGR: Samsung could face $ 15 billion fine for trying to ban iPhone, other Apple devices]






I bought a Nintendo Wii U for one reason and one reason only, and that’s to play and beat “Super Mario Bros. U.” I’ll probably end up returning the console after I’m done, because that’s how horrible the Wii U actually is.


[More from BGR: Five-year-old finds porn on refurbished Nintendo 3DS from GameStop]


First of all, the fact that Nintendo actually decided to ship this joke of a controller called the GamePad with a 6.2-inch touchscreen in the middle says it all. It only lasted for around two hours per charge over the week I’ve used it, and it’s big, clunky and made of glossy Nintendo plastic. The problem it, it has no charm. It feels thrown together to try to make a statement, one that says that Nintendo isn’t afraid of the iPads or Android tablets or iPhones or iPod touches, and that it too can take on touch just as it took on motion.


It fails miserably. And that’s just the controller.


The actual console is one that finally for the first time ever supports HDMI and HD graphics, yet Nintendo’s flagship game doesn’t look good in high-definition. The console’s UI is a mess, and let’s be honest, we are living in a time where we are so connected, where so much is shared across continents instantly, that real design transcends what country it was designed in.


When you see a beautiful iPhone app’s interface, there’s a good chance you couldn’t tell if it was designed by a company in San Francisco or Paris or Hong Kong. But Nintendo’s interface is blatantly Japanese, and it lacks any and all sophistication. It’s like all of Nintendo’s designers just gave up and are living in a time when Apple’s iOS devices and Google’s (GOOG) Android devices don’t exist, blissfully ignoring the threat that their company is facing from all angles.


The Wii U experience is so terrible that it took over an hour to update the software on the console recently, and apparently that wasn’t that bad. People have told me their updates took over 4 hours when performed closer to Christmas. Do you know what that 7-year-old is doing during those 4 hours you’re making him wait? Playing Temple Run or Angry Birds on his iPad mini. Way to go Nintendo.


I’ll go on record and say that I think this is the last video game console Nintendo will make for the home. I just don’t see the future here with hardware. Not by a mile.


Nintendo needs to realize that hardware is hardware and that Nintendo’s hardware isn’t special, it isn’t elegant and it isn’t thoughtful. It’s merely a delivery mechanism in a time where design has never been more important.


Nintendo is a great company, one that has invented so many great products, but sooner or later it will be forced to offer its titles on iOS devices and Android devices. It’s going to get to that point. There’s way too much revenue to be made — Nintendo isn’t Sega, and Sega is crushing it as a software-only company.


I just hope Nintendo follows suit sooner or later, because I have $ 9.99 ready to go for the Super Mario app on iOS.


This article was originally published by BGR


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NHL makes new offer; lockout enters critical stage


NEW YORK (AP) — The NHL made a new offer to the players' association, hoping to spark talks toward ending the long lockout and saving the hockey season.


Deputy commissioner Bill Daly said Friday the league presented its proposal Thursday and was waiting for a response. The sides haven't met in person since a second round of talks with a federal mediator broke down Dec. 13.


The lockout has reached its 104th day, and the NHL said it doesn't want a season of less than 48 games. That means a deal would need to be reached mid-January.


"We delivered to the union a new, comprehensive proposal for a successor CBA," Daly said in a statement Friday. "We are not prepared to discuss the details of our proposal at this time. We are hopeful that once the union's staff and negotiating committee have had an opportunity to thoroughly review and consider our new proposal, they will share it with the players. We want to be back on the ice as soon as possible."


A person familiar with key points of the offer told The Associated Press that the league proposed raising the limit of individual free-agent contracts to six years from five — seven years if a team re-signs its own player; raising the salary variance from one year to another to 10 percent, up from 5 percent; and one compliance buyout for the 2013-14 season that wouldn't count toward a team's salary cap but would be included in the overall players' share of income.


The person spoke on condition of anonymity because details of the new offer were not being discussed publicly.


The NHL maintained the deferred payment amount of $300 million it offered in its previous proposal, an increase from an earlier offer of $211 million. The initial $300 million offer was pulled off the table after negotiations broke off earlier this month.


The latest proposal is for 10 years, running through the 2021-22 season, with both sides having the right to opt out after eight years.


A conference call with the players' association's negotiating committee and its executive board was scheduled for Friday afternoon and was expected to last several hours.


The lockout has reached a critical stage, threatening to shut down a season for the second time in eight years. All games through Jan. 14, plus the Winter Classic and the All-Star game already have been called off. The next round of cuts could claim the entire schedule.


The NHL is the only North American professional sports league to cancel a season because of a labor dispute, losing the 2004-05 campaign to a lockout. A 48-game season was played in 1995 after a lockout stretched into January.


It is still possible this dispute could eventually be settled in the courts if the sides can't reach a deal on their own.


The NHL filed a class-action suit this month in U.S. District Court in New York in an effort to show its lockout is legal. In a separate move, the league filed an unfair labor practice charge with the National Labor Relations Board, contending bad-faith bargaining by the union.


Those moves were made because the players' association took steps toward potentially filing a "disclaimer of interest," which would dissolve the union and make it a trade association. That would allow players to file antitrust lawsuits against the NHL.


Union members voted overwhelmingly to give their board the power to file the disclaimer by Jan. 2. If that deadline passes, another authorization vote could be held to approve a later filing.


Negotiations between the NHL and the union have been at a standstill since talks ended Dec. 6. One week later, the sides convened again with federal mediators in New Jersey, but still couldn't make progress.


The sides have been unable to reach agreement on the length of the new deal, the length of individual player contracts, and the variance in salary from year to year. The NHL is looking for an even split of revenues with players.


The NHL pulled all previous offers off the table after the union didn't agree to terms on its last proposal without negotiation.


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Surgery Returns to NYU Langone Medical Center


Chang W. Lee/The New York Times


Senator Charles E. Schumer spoke at a news conference Thursday about the reopening of NYU Langone Medical Center.







NYU Langone Medical Center opened its doors to surgical patients on Thursday, almost two months after Hurricane Sandy overflowed the banks of the East River and forced the evacuation of hundreds of patients.




While the medical center had been treating many outpatients, it had farmed out surgery to other hospitals, which created scheduling problems that forced many patients to have their operations on nights and weekends, when staffing is traditionally low. Some patients and doctors had to postpone not just elective but also necessary operations for lack of space at other hospitals.


The medical center’s Tisch Hospital, its major hospital for inpatient services, between 30th and 34th Streets on First Avenue, had been closed since the hurricane knocked out power and forced the evacuation of more than 300 patients, some on sleds brought down darkened flights of stairs.


“I think it’s a little bit of a miracle on 34th Street that this happened so quickly,” Senator Charles E. Schumer of New York said Thursday.


Mr. Schumer credited the medical center’s leadership and esprit de corps, and also a tour of the damaged hospital on Nov. 9 by the administrator of the Federal Emergency Management Agency, W. Craig Fugate, whom he and others escorted through watery basement hallways.


“Every time I talk to Fugate there are a lot of questions, but one is, ‘How are you doing at NYU?’ ” the senator said.


The reopening of Tisch to surgery patients and associated services, like intensive care, some types of radiology and recovery room anesthesia, was part of a phased restoration that will continue. Besides providing an essential service, surgery is among the more lucrative of hospital services.


The hospital’s emergency department is expected to delay its reopening for about 11 months, in part to accommodate an expansion in capacity to 65,000 patient visits a year, from 43,000, said Dr. Andrew W. Brotman, its senior vice president and vice dean for clinical affairs and strategy.


In the meantime, NYU Langone is setting up an urgent care center with 31 bays and an observation unit, which will be able to treat some emergency patients. It will initially not accept ambulances, but might be able to later, Dr. Brotman said. Nearby Bellevue Hospital Center, which was also evacuated, opened its emergency department to noncritical injuries on Monday.


Labor and delivery, the cancer floor, epilepsy treatment and pediatrics and neurology beyond surgery are expected to open in mid-January, Langone officials said. While some radiology equipment, which was in the basement, has been restored, other equipment — including a Gamma Knife, a device using radiation to treat brain tumors — is not back.


The flooded basement is still being worked on, and electrical gear has temporarily been moved upstairs. Mr. Schumer, a Democrat, said that a $60 billion bill to pay for hurricane losses and recovery in New York and New Jersey was nearing a vote, and that he was optimistic it would pass in the Senate with bipartisan support. But the measure’s fate in the Republican-controlled House is far less certain.


The bill includes $1.2 billion for damage and lost revenue at NYU Langone, including some money from the National Institutes of Health to restore research projects. It would also cover Long Beach Medical Center in Nassau County, Bellevue, Coney Island Hospital and the Veterans Affairs hospital in Manhattan.


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China Toughens Restrictions on Internet Use





HONG KONG — The Chinese government issued new rules on Friday requiring Internet users to provide their real names to service providers, while assigning Internet companies greater responsibility for deleting forbidden postings and reporting them to the authorities.




The decision came as government censors have sharply stepped up restrictions on China’s international Internet traffic in recent weeks. The restrictions are making it harder for businesses to protect commercial secrets and for individuals to view overseas Web sites that the Chinese Communist Party deems politically sensitive.


The new regulations, issued by the Standing Committee of the National People’s Congress, allow Internet users to continue to adopt pseudonyms for their online postings, but only if they first provide their real names to service providers, a measure that could chill some of the vibrant discourse on the country’s Twitter-like microblogs. The authorities periodically detain and even jail Internet users for politically sensitive comments, such as calls for a multiparty democracy or accusations of impropriety by local officials.


Any entity providing Internet access, including over fixed-line or mobile phones, “should when signing agreements with users or confirming provision of services, demand that users provide true information about their identities,” the committee ordered.


In recent weeks, Internet users in China have exposed a series of sexual and financial scandals that have led to the resignations or dismissals of at least 10 local officials. International news media have also published a series of reports in recent months on the accumulation of wealth by the family members of China’s leaders, and some Web sites carrying such reports, including Bloomberg’s and the English- and Chinese-language sites of The New York Times, have been assiduously blocked, while Internet comments about them have been swiftly deleted.


The regulations issued Friday build on a series of similar administrative guidelines and municipal rules issued over the past year. China’s mostly private Internet service providers have been slow to comply with them, fearing the reactions of their customers. The committee’s decision has much greater legal force, and puts far more pressure on Chinese Internet providers to comply more quickly and more comprehensively, Internet specialists said.


In what appeared to be an effort to make the decision more palatable to the Chinese public, the committee also included a mandate for businesses in China to be more cautious in gathering and protecting electronic data.


“Nowadays on the Internet there are very serious problems with citizens’ personal electronic information being recklessly collected, used without approval, illegally disclosed, and even traded and sold,” Li Fei, a deputy director of the committee’s legislative affairs panel, said on Friday at a news conference in Beijing. “There are also a large number of cases of invasive attacks on information systems to steal personal electronic information, as well as lawbreaking on the Internet through swindles and through defaming and slandering others.”


Mr. Li denied that the government was seeking to prevent the exposure of corruption.


“When citizens exercise these rights according to the law, no organization or individual can use any reason or excuse to interfere, and cannot suppress them or exact revenge,” he said. “At the same time, when citizens exercise their rights, including through use of the Internet, they should stay within the bounds of the Constitution and the laws, and must not harm the legitimate rights and interests of the state, society, the collective or of other citizens.”


A spokesman for the National People’s Congress said that 145 members of the committee voted in favor of the new rules, with 5 abstaining and 1 voting against them.


The requirement for real names appeared to be aimed particularly at cellphone companies and other providers of mobile Internet access. At the news conference, an official from the Ministry of Industry and Information Technology, Zhao Zhiguo, said that nearly all fixed-line services now had real-name registration, but that only about 70 percent of mobile phones were registered under real names.


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Iran’s Only Female Cabinet Minister Dismissed





Iran’s president on Thursday dismissed his health minister, the only woman to serve in the cabinet since the 1979 Islamic revolution, after she publicly criticized the government’s response to acute shortages of medicine imports, an indirect consequence of the Western sanctions imposed on the country.




Accounts in the state-run news media of the dismissal of the minister, Marzieh Vahid-Dastjerdi, did not provide an explanation for it. Iran’s Press TV Web site said President Mahmoud Ahmadinejad had appointed a caretaker health minister, Mohammad Hassan Tariqat-Monfared, and had told him in a presidential decree that the reduction of people’s health care expenses was among “the main priorities of this important ministry.”


Dr. Vahid-Dastjerdi, a gynecologist, was appointed in 2009 and is considered an advocate of women’s rights in Iranian society. She spoke out last month, apparently angering the president, by saying that an allocation in the budget of foreign currency needed to purchase medicines abroad was inadequate.


“I have heard that luxury cars have been imported with subsidized dollars, but I don’t know what happened to the dollars that were supposed to be allocated for importing medicine,” Dr. Vahid-Dastjerdi said on state television, according to a translation of her remarks reported by Reuters.


Absent such an allocation, she said, it was necessary to impose a large increase in the price of medicines, which would add to the inflationary pressures already afflicting the economy because of a plunge in value this year of the Iranian currency, the rial. Mr. Ahmadinejad opposed the price increase.


Many economists have attributed the rial’s depreciation to Iran’s increased isolation, a consequence of the penalties imposed by the United States and European Union to pressure Iran to stop enriching uranium for its disputed nuclear energy program. Some of Mr. Ahmadinejad’s critics in Iran have also blamed the currency problems on what they call his economic mismanagement.


The medicine shortage in Iran has become an urgent problem because many Western-made drugs are increasingly hard to obtain. Under the sanctions, a broad Western ban on many financial transactions with Iran has dissuaded many foreign companies from doing business with the country, even though medicines are among items exempted from the sanctions.


Recently, the president of the Iranian Academy of Medical Sciences, Seyed Alireza Marandi, bitterly complained about the medical impact of the sanctions in a letter to Ban Ki-moon, the United Nations secretary general. Dr. Marandi called the sanctions brutal measures that had increased mortality rates “as a result of the unavailability of essential drugs and shortages of medical supplies and equipment,” according to a report by the Fars News Agency.


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Apple CEO’s pay takes big hit vs. record 2011 package






NEW YORK (Reuters) – Apple Inc CEO Tim Cook’s 2012 compensation package of just over $ 4 million is a huge cut on paper for the top executive of the most valuable U.S. corporation, after a 2011 package fattened by more than $ 376 million in long-term stock awards.


Cook received the largest single pay package awarded to a company CEO in about a decade when he replaced Apple‘s legendary co-founder, Steve Jobs, shortly before Jobs’ death in October 2011.






The maker of the iPhone and iPad made the 2012 compensation disclosures in a regulatory filing on Thursday. Cook, who is in his early 50s, joined Apple in 1998 and became CEO in August 2011.


Virtually all of Cook’s $ 376 million bonus in 2011 was in stock awards that will vest in two chunks – one in 2016 and the other in 2021. This structure was intended to keep Jobs’ longtime lieutenant at the helm for many years.


In terms of base salary, Cook actually received a 50 percent increase to $ 1.4 million for 2012, and the same 200 percent bonus that other top Apple executives like CFO Peter Oppenheimer earned, Apple said in a regulatory filing on Thursday.


The 2012 compensation package for Cook also pales in comparison with his 2010 pay, which was 14 times higher, when he served as chief operating officer.


But Tim Ghriskey, chief investment officer of Solaris Group – which counts Apple stock as the biggest holding among the approximately $ 2 billion it manages – said Cook’s package was “normal CEO compensation.”


For example, Yahoo Inc’s CEO, Marissa Mayer, a former Google Inc high-flyer hired this year to try to turn around the struggling Internet icon, won a pay package worth more than $ 70 million. Despite her lack of a CEO track record, her basic pay is comparable to Cook’s, with about $ 1 million in annual salary and up to $ 2 million in an annual bonus.


Oracle Corp’s Larry Ellison, one of the most highly paid chief executives in the United States – and also the world’s sixth-richest man, according to Forbes – received total compensation for the year ended May 31, 2012, of $ 96.2 million – almost all of it in stock options.


That compared with $ 77.6 million for Ellison in the prior year.


Cook’s longtime boss, Jobs, famously received $ 1 a year in salary in the three years before he stepped down, though in 2000 he too received a stock option that analysts say was valued at almost $ 600 million at the time.


Cook will not receive any stock awards for 2012, Apple said in Thursday’s filing.


The 2012 package includes a salary of $ 1.4 million and a nonequity bonus of $ 2.8 million. Cook’s base salary actually increased in 2012 from the $ 900,000 he earned in 2011.


While Apple’s shares are roughly 35 percent higher than when Cook became CEO, they have fallen more than 27 percent since October, when they hit a $ 700.10 high. The stock has declined amid investor worries about intensifying competition in the mobile phone market and growth prospects in important markets including China.


Apple shares were down 1.3 percent at $ 506.35 on the Nasdaq on Thursday afternoon.


(Reporting by Sinead Carew and Liana Baker in New York, Jim Finkle and Tim McLaughlin in Boston and Edwin Chan in San Francisco,; editing by Kenneth Barry and Matthew Lewis)


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Net loss: Brooklyn fires coach Avery Johnson


NEW YORK (AP) — Avery Johnson was fired Thursday as coach of the Brooklyn Nets, who have fallen to .500 in their season of new surroundings and elevated expectations.


General manager Billy King announced the dismissal in a statement. Assistant P.J. Carlesimo will coach the Nets at home Friday against Charlotte, according to someone with knowledge of the plans. The person spoke on condition of anonymity because details were to be provided at a news conference later in the day.


"The Nets ownership would like to express thanks to Avery for his efforts and to wish him every success in the future," owner Mikhail Prokhorov said in a statement.


After a strong start to their first season in Brooklyn, the Nets have lost 10 of 13 games to fall well behind the first-place New York Knicks, the team they so badly want to compete with in their new home.


But after beating the Knicks in their first meeting Nov. 26, probably the high point of Johnson's tenure, the Nets went 5-10 and frustrations have been mounting.


The Nets were embarrassed by Boston on national TV on Christmas, then were routed by Milwaukee 108-93 on Wednesday night for their fifth loss in six games.


Star guard Deron Williams recently complained about Johnson's offense, and Nets CEO Brett Yormark took to Twitter after the loss to Celtics to voice his displeasure with the performance.


Brooklyn started the season 11-4, winning five in a row to end November, when Johnson was Eastern Conference coach of the month. But he couldn't do anything to stop this slump, one the Nets never anticipated after a $350 million summer spending spree they believed would take them toward the top of their conference.


Johnson has been the Nets' coach for a little more than two seasons. He went 60-116 with the Nets, who moved from New Jersey to Brooklyn to start the 2012-13 season. Johnson coached the Dallas Mavericks to a spot in the NBA Finals in 2006.


This is the NBA's second coaching change this season following the dismissal of Mike Brown by the Los Angeles Lakers.


Johnson arrived in New Jersey with a 194-70 record, a .735 winning percentage that was the highest in NBA history, but had little chance of success in his first two seasons while the Nets focused all their planning on the move to Brooklyn.


They looked to make a splash this summer when they re-signed Williams and fellow starters Gerald Wallace, Brook Lopez and Kris Humphries, traded for Atlanta All-Star Joe Johnson, and added veteran depth with players such as Reggie Evans, C.J. Watson and Andray Blatche.


Johnson didn't have a contract beyond this season but seemed to have the confidence of Prokhorov, the Russian billionaire who before the season said he had faith in "the Avery defense system."


Some predicted the Nets would finish as high as second in the East behind defending champion Miami, and the projections seemed warranted when the Nets started quickly amid much fanfare. But all the good publicity faded in recent weeks once the losing started.


Williams, who has struggled this season, stirred the waters when he expressed his preference for the offense he ran under Jerry Sloan in Utah before a loss to the Jazz. Williams and Johnson, nicknamed "Brooklyn's Backcourt" and expected to be one of the best in the NBA, have shot poorly and rarely meshed.


The Nets were embarrassed near the end of their 93-76 loss to Boston, when fans exited early amid a chant of "Let's go Celtics!"


"Nets fans deserved better," Yormark tweeted after the game. "The entire organization needs to work harder to find a solution. We will get there."


Not under Johnson, though.


The Nets should be able to entice a big-name coach with Prokhorov's billions and the chance to play in a major market at Barclays Center, the $1 billion arena that has drawn praise in the city and from visiting teams.


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Measles: Measles Epidemic Is Spreading in Central Africa


Jehad Nga for The New York Times


An internally displaced persons camp in Goma, in the Democratic Republic of Congo. In addition to recent violence in the country, a spreading measles epidemic is further endangering the lives of thousands of children there.







A large measles epidemic is spreading in Central Africa, endangering the lives of thousands of children, the medical charity Doctors Without Borders warned last week.




Since October, the charity has vaccinated more than 226,000 children in the eastern part of the Democratic Republic of Congo. The organization has also treated nearly 13,000 Congolese for the effects of the disease.


Measles is very contagious. In places where many children are malnourished and vitamin-deficient, it kills 1 percent to15 percent of those who don’t receive medical care, Doctors Without Borders estimated. (Even in the United States in the 1990s, although cases were rare, the fatality rate was 0.3 percent, according to the Centers for Disease Control and Prevention. In AIDS patients, the rate is 30 percent.)


The eastern Congo basin has serious shortages of medical workers and of drugs. While there is no treatment for measles itself, antibiotics can save those who develop pneumonia, meningitis or other secondary infections. Measles can also cause blindness by scarring the eyeball.


The outbreak is taking place despite enormous success against the disease worldwide. According to a study released earlier this year, deaths from measles have dropped by almost 75 percent since 2000.


Most of the lives saved were in Africa and India. Measles shots are often cited as one of the chief reasons that deaths of children under age 5 around the world have fallen steadily.


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Senate Leader Says Deal Is Unlikely Before Fiscal Deadline





WASHINGTON — Senator Harry Reid of Nevada, the majority leader, warned Thursday that there was scant time to put together a Congressional deal to avert the impending fiscal crisis and that no resolution was in sight.







T.J. Kirkpatrick for The New York Times

Senator Harry Reid arrived at the Capitol on Thursday in Washington.







“I have to be very honest,” Mr. Reid said as the Senate convened in an unusual session between Christmas and New Year’s Day. “I don’t know time-wise how it can happen now.”


Mr. Reid offered his pessimistic assessment shortly before President Obama, cutting his vacation short, arrived back in Washington on Air Force One. White House officials said that before leaving Hawaii, Mr. Obama had spoken separately by phone with each of the four Congressional leaders about the status of negotiations, but they gave no details of the discussion.


Mr. Obama is expected to invite all four lawmakers to meet on Friday. In a related development, House Republicans were told to return to Washington on Sunday. Republican senators were planning to convene at the Capitol — normally somnolent during Christmas week — to strategize.


On the Senate floor Thursday, Mr. Reid excoriated House Republicans for failing to consider a Senate-passed measure that would extend lower tax rates on household income up to $250,000. He urged House members to return to the Capitol to put together at least a modest deal to avoid the more than half-a-trillion dollars in automatic tax increases and spending cuts set to begin in January.


“The American people are waiting for the ball to drop,” Mr. Reid said, “but it’s not going to be a good drop.”


A spokesman for Senator Mitch McConnell, Republican of Kentucky and the minority leader, confirmed that he had spoken with the president, and said that Mr. McConnell was “happy to review what the president has in mind.” But the spokesman, Don Stewart, said Senate Democrats had not come ahead with a plan.


“When they do, members on both sides of the aisle will review the legislation and make decisions on how best to proceed,” Mr. Stewart said.


Mr. Reid said that absent a move from Republicans, the Senate would move forward this week on a national security measure concerning espionage, as well as a bill to help states that have suffered hurricane damage, with multiple votes possible.


“We are here in Washington working,” Mr. Reid said, “while the members of the House of Representatives are out watching movies and watching their kids play soccer and basketball and doing all kinds of things. They should be here.”


Senators, frustrated, pessimistic and in some cases downright miserable, returned to Washington with no clear fiscal agenda. Senator Ben Nelson, a retiring Democrat of Nebraska, arrived shortly after midnight on Thursday on a flight that was delayed more than four hours. As he walked through the airport, he lamented the deteriorating political comity that he has observed during two terms in the Senate and two terms as a Democratic governor of a conservative state.


“There are folks who are elected who have come here with an agenda to do nothing and want to stop everything,” Mr. Nelson said in an interview. “It may be the new norm – blocking everything.”


For Mr. Nelson, who decided against seeking a third term, the looming fiscal crisis would be the final legislative act of a political career built around a bipartisan voting record. He said he was not confident that a real deal could be reached that would be acceptable to both sides, considering that Congress is filled with many people “who didn’t accept the 2008 presidential election and haven’t accepted the 2012 election either.”


Jeff Zeleny contributed reporting.



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United Arab Emirates Arrests Suspects in Terror Plots





DUBAI, United Arab Emirates (Reuters) — Security forces in the United Arab Emirates have arrested members of a cell made up of militants from Saudi Arabia and the emirates who were planning to carry out attacks in both countries and in other states, the official Emirates News Agency said on Wednesday.




The federation of seven emirates, a major oil exporter and an ally of the United States, has had no attacks by Al Qaeda or other terrorist groups. But Islamist sentiment has risen in recent years, and Dubai, a business and tourism hub that attracts many Westerners, could make an attractive target for militants, analysts say.


The suspects had acquired materials and equipment for use in what the news agency called terrorist operations.


“The security authorities in the U.A.E., in coordination with the related security parties in Saudi Arabia, announced the arrest of an organized cell from the deviant group that was planning to carry out actions against national security of both countries and some brotherly states,” the agency said, without elaborating.


The phrase “deviant group” is often used by the authorities in Saudi Arabia to describe Al Qaeda.


In August, the Saudi authorities arrested a group of militants in Riyadh — mostly Yemeni nationals — suspected of having links to Al Qaeda. Thousands of people believed to be militants have been arrested since dozens were killed in terrorist attacks between 2003 and 2006 on Saudi residential compounds and offices for foreign workers and on government facilities.


The United States has poured aid into Yemen to stem the threat of attacks from the group Al Qaeda in the Arabian Peninsula and to try to prevent any spillover of violence into Saudi Arabia, the world’s top oil exporter.


In 2010, Al Qaeda in the Arabian Peninsula, formed with the merger of Al Qaeda’s Yemeni and Saudi branches, said it was behind a plot to send two parcel bombs to the United States. The bombs were intercepted in Britain and Dubai.


Though the emirates have escaped much of the upheaval that has shaken the Arab world, the authorities have moved swiftly to stem any sign of political dissent, detaining more than 60 Islamists this year over suspected threats to state security and links to foreign groups.


Those detainees, who belong to an Islamist group called Al-Islah, have confessed to setting up a secret organization with an armed force whose aim was to take power and establish an Islamic state, the local news media reported in September. The group denied the accusations.


Many of the detained Islamists are from the more religiously conservative northern emirates like Sharjah and Ras al-Khaimah, which produced one of the Sept. 11 hijackers.


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Netflix blames Amazon for Christmas Eve outage






NEW YORK (Reuters) – An outage at one of Amazon‘s web service centers hit users of Netflix Inc‘s streaming video service on Christmas Eve and was not fully resolved until Christmas Day, a spokesman for the movie rental company said on Tuesday.


The outage impacted Netflix subscribers across Canada, Latin America and the United States, and affected various devices that enable users to stream movies and television shows from home, Netflix spokesman Joris Evers said. Such devices range from gaming consoles like the Nintendo Wii and PlayStation 3 to Blu-ray DVD players.






Netflix, which is based in Los Gatos, California, has 30 million streaming subscribers worldwide, of which more than 27 million are in the Americas region that was exposed to the outage and could have potentially been affected, Evers said.


Evers said the issue was the result of an outage at an Amazon Web Services‘ cloud computing center in Virginia and started at about 12:30 p.m. PST (2030 GMT) on Monday and was fully restored before 8:00 a.m. PST Tuesday morning, although streaming was available for most users by 11:00 p.m. PST on Monday.


The event marks the latest in a series of outages from Amazon Web Services, with one occurring in April of last year that knocked out such sites as Reddit and Foursquare.


“We are investigating exactly what happened and how it could have been prevented,” Evers of Netflix said.


“We are happy that people opening gifts of Netflix or Netflix capable devices can watch TV shows and movies and apologize for any inconvenience caused last night,” he added.


Officials at Amazon Web Services were not available for comment. Evers, the Netflix spokesman, declined to comment on the company’s contracts with Amazon.


(Reporting by Sam Forgione; Editing by Leslie Gevirtz and Matt Driskill)


Internet News Headlines – Yahoo! News





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Red Sox get All-Star closer Hanrahan from Pirates


BOSTON (AP) — The Red Sox have acquired All-Star closer Joel Hanrahan from the Pittsburgh Pirates in a six-player deal.


Boston completed the trade Wednesday, also receiving infielder Brock Holt. The Red Sox gave up right-handers Mark Melancon and Stolmy Pimentel, infielder Ivan DeJesus Jr. and first baseman-outfielder Jerry Sands.


Over the past two seasons, the right-handed Hanrahan had 76 saves, fourth most in the National League, and a 2.24 ERA. Last season, he was 5-2 with a 2.72 ERA and 36 saves.


Holt spent most of last season at Double-A Altoona, then hit .292 in 24 games with the Pirates, all in September.


Melancon was 0-2 with a 6.20 ERA in 41 relief appearances in his only season with Boston. Pimentel spent the season at Double-A Portland. Sands and DeJesus were obtained in a trade that sent Josh Beckett, Carl Crawford and Adrian Gonzalez to the Los Angeles Dodgers on Aug. 25.


The Red Sox also announced the signing of free agent shortstop Stephen Drew, who agreed to a one-year contract early last week. That reported $9.5 million deal was contingent on the former Oakland Athletic and Arizona Diamondback passing a physical.


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Well: Exercise and the Ever-Smarter Human Brain

Anyone whose resolve to exercise in 2013 is a bit shaky might want to consider an emerging scientific view of human evolution. It suggests that we are clever today in part because a million years ago, we could outrun and outwalk most other mammals over long distances. Our brains were shaped and sharpened by movement, the idea goes, and we continue to require regular physical activity in order for our brains to function optimally.

Phys Ed

Gretchen Reynolds on the science of fitness.

The role of physical endurance in shaping humankind has intrigued anthropologists and gripped the popular imagination for some time. In 2004, the evolutionary biologists Daniel E. Lieberman of Harvard and Dennis M. Bramble of the University of Utah published a seminal article in the journal Nature titled “Endurance Running and the Evolution of Homo,” in which they posited that our bipedal ancestors survived by becoming endurance athletes, able to bring down swifter prey through sheer doggedness, jogging and plodding along behind them until the animals dropped.

Endurance produced meals, which provided energy for mating, which meant that adept early joggers passed along their genes. In this way, natural selection drove early humans to become even more athletic, Dr. Lieberman and other scientists have written, their bodies developing longer legs, shorter toes, less hair and complicated inner-ear mechanisms to maintain balance and stability during upright ambulation. Movement shaped the human body.

But simultaneously, in a development that until recently many scientists viewed as unrelated, humans were becoming smarter. Their brains were increasing rapidly in size.

Today, humans have a brain that is about three times larger than would be expected, anthropologists say, given our species’ body size in comparison with that of other mammals.

To explain those outsized brains, evolutionary scientists have pointed to such occurrences as meat eating and, perhaps most determinatively, our early ancestors’ need for social interaction. Early humans had to plan and execute hunts as a group, which required complicated thinking patterns and, it’s been thought, rewarded the social and brainy with evolutionary success. According to that hypothesis, the evolution of the brain was driven by the need to think.

But now some scientists are suggesting that physical activity also played a critical role in making our brains larger.

To reach that conclusion, anthropologists began by looking at existing data about brain size and endurance capacity in a variety of mammals, including dogs, guinea pigs, foxes, mice, wolves, rats, civet cats, antelope, mongeese, goats, sheep and elands. They found a notable pattern. Species like dogs and rats that had a high innate endurance capacity, which presumably had evolved over millenniums, also had large brain volumes relative to their body size.

The researchers also looked at recent experiments in which mice and rats were systematically bred to be marathon runners. Lab animals that willingly put in the most miles on running wheels were interbred, resulting in the creation of a line of lab animals that excelled at running.

Interestingly, after multiple generations, these animals began to develop innately high levels of substances that promote tissue growth and health, including a protein called brain-derived neurotrophic factor, or BDNF. These substances are important for endurance performance. They also are known to drive brain growth.

What all of this means, says David A. Raichlen, an anthropologist at the University of Arizona and an author of a new article about the evolution of human brains appearing in the January issue of Proceedings of the Royal Society Biology, is that physical activity may have helped to make early humans smarter.

“We think that what happened” in our early hunter-gatherer ancestors, he says, is that the more athletic and active survived and, as with the lab mice, passed along physiological characteristics that improved their endurance, including elevated levels of BDNF. Eventually, these early athletes had enough BDNF coursing through their bodies that some could migrate from the muscles to the brain, where it nudged the growth of brain tissue.

Those particular early humans then applied their growing ability to think and reason toward better tracking prey, becoming the best-fed and most successful from an evolutionary standpoint. Being in motion made them smarter, and being smarter now allowed them to move more efficiently.

And out of all of this came, eventually, an ability to understand higher math and invent iPads. But that was some time later.

The broad point of this new notion is that if physical activity helped to mold the structure of our brains, then it most likely remains essential to brain health today, says John D. Polk, an associate professor of anthropology at the University of Illinois at Urbana-Champaign, and co-author, with Dr. Raichlen, of the new article.

And there is scientific support for that idea. Recent studies have shown, he says, that “regular exercise, even walking,” leads to more robust mental abilities, “beginning in childhood and continuing into old age.”

Of course, the hypothesis that jogging after prey helped to drive human brain evolution is just a hypothesis, Dr. Raichlen says, and almost unprovable.

But it is compelling, says Harvard’s Dr. Lieberman, who has worked with the authors of the new article. “I fundamentally agree that there is a deep evolutionary basis for the relationship between a healthy body and a healthy mind,” he says, a relationship that makes the term “jogging your memory” more literal than most of us might have expected and provides a powerful incentive to be active in 2013.

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Irish Travelers, Gathering for Christmas, Flood a Town





RATHKEALE, Ireland — Christmas in Ireland is a time of homecomings, with joyous family reunions at airports and ferry piers. But the largest single gathering of all briefly turns this little town into the only place in Ireland where armed police officers patrol the streets 24 hours a day to deter internecine feuds and other disorderly conduct.




Usually, Rathkeale is an unremarkable rural town in County Limerick, but every year at this time, cavalcades of Irish nomads — known as travelers — return here to the place they regard as their spiritual home. It is an opportunity to hold fairy-tale weddings and christenings, and to settle old scores. The highly mobile families are deeply interwoven through marriage and kinship, and extremely suspicious of outsiders and the authorities.


For about six weeks of the year, the town’s population swells to 4,500 from 1,500, and ostentatious displays of wealth are common. Expensive sport utility vehicles create gridlock in the narrow streets and alleyways, trailers and mobile homes clutter the sidewalks and young men speed through the surrounding country lanes in their sports cars.


A long history of violence between clans hangs like a cloud over the travelers. When they congregate at Christmas, brawls involving knives, cudgels, iron bars and screwdrivers have been known to erupt, and traffic violations multiply. Last year alone, the police seized 30 vehicles for various offenses.


Over the past couple of decades, the travelers have bought or built houses in Rathkeale. The rows of extravagant, mock-Georgian mansions that have sprung up just off the main street are boarded up for most of the year but come alive around Christmas when their owners return, mainly from Britain but also from increasingly far-flung places.


The Rathkeale travelers have long had a reputation for business acumen, making fortunes by developing property, dealing antiques, trading in scrap metal and asphalt paving. But in recent years, a growing body of evidence has fueled suspicions that not all of the money flowing into Rathkeale comes from strictly legal transactions and that the property deals are a form of money laundering.


“People won’t say a bad word against them in public because they’re afraid of getting a bottle through the window — or something a lot worse,” said one Rathkeale resident, who did not want to be named. “Who really believes tarring driveways or fixing gutters gets you those massive houses or flashy cars?”


Certainly, travelers with links to Rathkeale have made headlines for all the wrong reasons in recent years.


Five members of one family were sentenced to prison this month after being found guilty of forcing vulnerable men to work for them under virtually slavelike conditions. According to court documents, the British police believe that the family owns several properties in Rathkeale, and the British authorities are working with their Irish counterparts to seize the family’s assets.


Others with Rathkeale connections have been jailed for various offenses from Australia to Iceland, including smuggling and handling counterfeit goods. In 2010, two men were caught trying to buy illegal black rhino horns from undercover federal agents.


Edward Grace, the deputy chief of law enforcement with the United States Fish and Wildlife Service, said the agency expected “more indictments of members of the Rathkeale Irish Traveler group.”


“These Irish Traveler gang members are the middlemen in the operation that also involves Chinese and Asian gangs,” he said. “They have access to large amounts of cash to buy the horns, and they have the network to sell them on at exorbitant prices. Some people will say, ‘What’s the harm here? These animals are already dead.’ But they are fueling an illegal trade and that means more incentive to kill endangered species.”


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Rondo leads Celtics past Nets 93-76


NEW YORK (AP) — Rajon Rondo scored 19 points in his first full game against Brooklyn this season, and the Boston Celtics beat the Nets 93-76 on Tuesday in another game with some heated moments between the division rivals.


Rondo, sidelined in the first meeting and thrown out of the second after shoving Nets forward Kris Humphries into the courtside seats, outplayed counterpart Deron Williams and helped the Celtics take control early.


Rookie Jared Sullinger tied a career high with 16 points and Jeff Green had 15 for the Celtics (14-13), who avoided falling under .500 with just their second victory in six games.


Gerald Wallace and Brook Lopez each scored 15 for the Nets, who have lost four of five.


The Celtics took control with a 23-5 run in the second quarter. They had 11 assists on 13 baskets and outscored the Nets 34-18 in the period.


A month after the teams scuffled in Boston, there was another skirmish in the fourth quarter that resulted in four technical fouls, but that was the most fight the Nets put up in a disappointing performance on the national stage of the Christmas opener. They were never in the game after the first 20 minutes, and their fans headed to the exits with under 2 minutes left as a "Let's go Celtics!" chant broke out.


Williams had only 10 points on 3-of-7 shooting and Joe Johnson, his partner in a high-priced backcourt, shot 4 of 14 for his 12 points.


Boston's Kevin Garnett had eight points and 10 rebounds on the day he tied Charles Oakley for 15th place on the NBA's career list with his 1,282nd game. He was also front and center when things got testy.


Wallace was fouled with 9:31 remaining and appeared to hold onto Garnett's uniform to balance himself and not fall. But Garnett objected to how long Wallace hung on, and they said something to each other as they tried to push themselves free. That led to technical fouls on the two, along with Andray Blatche and Courtney Lee.


Sullinger delivered a flagrant foul on Wallace a few minutes later, but there was nothing further.


In the Nets' Nov. 28 victory in Boston, Rondo, Humphries and Wallace were ejected.


It was the second quarter of that game where things got away from the Celtics, and Rondo's frustrations soon followed. He shoved Humphries after the Nets forward fouled Garnett, ruining the point guard's chance to extend what was then a 37-game streak with double digit assists by finishing with three. He had five assists and six rebounds Tuesday.


This time, the second period belonged to the guys in green.


With the Celtics down three, Green had six points in a 10-0 run that made it 36-29. After Johnson's basket, Boston answered with a 13-3 spurt. Jason Terry made a 3-pointer before Rondo converted a three-point play to push the Celtics' lead to 49-34 with 3:56 to go.


Notes: As with everyone playing on Christmas, players, coaches and referees wore green ribbons in tribute to the families of Sandy Hook Elementary School. ... Humphries was out with an abdominal strain and will be re-evaluated after the Nets return from Milwaukee. He had mostly been a starter but then didn't play at all Sunday against Philadelphia. ... Feeling Avery Bradley isn't ready yet, Celtics coach Doc Rivers decided not to bring the guard on this four-game road trip so he can continue working his way back from shoulder surgery in Boston. Rivers said the shoulder is strong but that Bradley has had only 2½ practices.


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Chicken Farms Try Oregano as Antibiotic Substitute


Jessica Kourkounis for The New York Times


Bell & Evans' chickens at a farm in Pennsylvania. Products at Bell & Evans have long been free of antibiotics, contributing to the company’s financial success as consumers have demanded purer foods.







FREDERICKSBURG, Pa. — The smell of oregano wafting from Scott Sechler’s office is so strong that anyone visiting Bell & Evans these days could be forgiven for wondering whether Mr. Sechler has forsaken the production of chicken and gone into pizza.




Oregano lies loose in trays and tied into bunches on tabletops and counters, and a big, blue drum that held oregano oil stands in the corner. “Have you ever tried oregano tea?” Mr. Sechler asked, mashing leaves between his broad fingers.


Off and on over the last three years or so, his chickens have been eating a specially milled diet laced with oregano oil and a touch of cinnamon. Mr. Sechler swears by the concoction as a way to fight off bacterial diseases that plague meat and poultry producers without resorting to antibiotics, which some experts say can be detrimental to the humans who eat the meat. Products at Bell & Evans, based in this town about 30 miles east of Harrisburg, have long been free of antibiotics, contributing to the company’s financial success as consumers have demanded purer foods.


But Mr. Sechler said nothing he had used as a substitute in the past worked as well as oregano oil. “I have worried a bit about how I’m going to sound talking about this,” he said. “But I really do think we’re on to something here.”


Skeptics of herbal medicines abound, as any quick Internet search demonstrates. “Oil of oregano is a perennial one, advertised as a cure for just about everything,” said Scott Gavura, a pharmacist in Toronto who writes for the Web site Science-Based Medicine. “But there isn’t any evidence, there are too many unanswered questions and the only proponents for it are the ones producing it.”


Nonetheless, Mr. Gavura said he would welcome a reduction in the use of antibiotics in animals. At the same time, consumers are growing increasingly sophisticated about the content of the foods they eat.


Data on sales of antibiotic-free meat is hard to come by, but the sales are a tiny fraction of the overall meat market. Sales in the United States of organic meat, poultry and fish, which by law must be raised without antibiotics, totaled $538 million in 2011, according to the Organic Trade Association. By comparison, sales of all beef that year were $79 billion.


Still, retailers like Costco, Whole Foods and Trader Joe’s, as well as some restaurant chains, complain that they cannot get enough antibiotic-free meat.


Noodles & Company, a fast-growing chain of more than 300 restaurants, recently added antibiotic-free pork to the choices of ingredients that customers can add to their made-to-order pastas. It ensured its supply by ordering cuts of meat that were not in relatively high demand and by committing in advance to buy a year’s worth, said Dan Fogarty, its executive vice president for marketing.


“We’re deliberately voting with our pocketbooks,” he said.


In a nationwide telephone survey of 1,000 adults in March, more than 60 percent told the Consumer Reports National Research Center that they would be willing to pay at least 5 cents a pound more for meat raised without antibiotics.


“Before, it was kind of a nice little business, and while it’s still microscopic in the grand scheme of things, we’re seeing acceptance from retailers across the country, not just in California and on the East Coast,” said Stephen McDonnell, founder and chief executive of Applegate, an organic and natural meats company.


Mr. McDonnell said a confluence of trends, from heightened interest in whole and natural foods to growing concerns about medical problems like diabetes, obesity and gluten allergies, were contributing to the demand for antibiotic-free meat.


There is growing concern among health care experts and policy makers about antibiotic resistance and the rise of “superbugs,” bacteria that are impervious to one or more antibiotics. Those bacteria can be passed on to consumers, who eat meat infected with them and then cannot be treated.


In November, the Centers for Disease Control and Prevention and 25 national health organizations and advocacy groups issued a statement on antibiotics that, among other things, called for “limiting the use of medically important human antibiotics in food animals” and “supporting the use of such antibiotics in animals only for those uses that are considered necessary for assuring animal health.”


In 2011, there were several prominent recalls involving bacterial strains that are resistant to antibiotics, including more than 60 million pounds of ground beef contaminated with salmonella Typhimurium and about 36 million pounds of ground turkey spoiled with salmonella Heidelberg.


Consumer Reports released a study last month that found the bacteria Yersinia enterocolitica in 69 percent of 198 pork chop and ground pork samples bought at stores around the country. Some of the bacteria were resistant to one or more antibiotics.


Analysis of Food and Drug Administration data by the Center for Science in the Public Interest found that 80 percent of all antibiotics sold in the United States are used in animals. The majority of those antibiotics are used to spur growth or prevent infections from spreading in the crowded conditions in which most animal production takes place today.


The European Union has banned the use of antibiotics to accelerate growth, and the European Parliament is pushing to end their use as tools to prevent disease as well.


The oregano oil product Mr. Sechler uses, By-O-Reg Plus, is made by a Dutch company, Ropapharm International. In the late 1990s, Bayer conducted trials on the product, known as Ropadiar in Europe, comparing its ability to control diarrhea in piglets caused by E. coli with that of four of the company’s products.


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U.S. Civilian Is Killed at Police Headquarters in Kabul





KABUL, Afghanistan — A female police sergeant shot and killed an American civilian adviser at police headquarters in Kabul on Monday, Afghan police officials said, breaking a relative lull in the so-called insider killings that have strained the relationship between Americans and Afghans here.




The American victim was identified as Joseph Griffin, 49, of Mansfield, Ga., who had worked for DynCorp International as a police trainer since July 2011, according to a DynCorp spokeswoman, Ashley Burke.


Afghan officials identified the suspect as a woman named Nargis, a 33-year-old sergeant in the national police force who worked in the Interior Ministry’s legal and gender equality department, and whose husband is also a member of the police force.


A person at Kabul police headquarters, speaking on the condition of anonymity because he was not authorized to release information, said the attacker had shot the American adviser in the head at close range with a pistol and then was immediately arrested by other Afghan police officers. The person added that both American and Afghan officials were questioning her, and he said she was distraught. The police said they did not believe the attack was related to terrorism and that the suspect had no known connections with insurgents.


The Afghan news station TOLO cited Afghan officials as saying that the woman, who had crossed multiple police checkpoints before she fired her gun, had graduated from the national police academy in 2008, in one of its first female classes.


The effort to recruit and train female police officers has been fraught with difficulty. Eupol, the European police organization active in police training here, says there are only 380 female police officers in Kabul, and even fewer in the provinces, despite a goal by the Interior Ministry of recruiting 5,000 by the end of 2014.


Insider attacks, in which members of the Afghan security services have turned against their foreign allies, have greatly increased in the past year, with 61 American and other coalition members killed, not including the episode on Monday, compared with 35 deaths the previous year, according to NATO figures.


Monday’s attack — the first insider attack known to be committed by a woman — came after a lull in insider shootings after the military instituted a series of precautions meant to reduce them. The most recent episode was on Nov. 11, when a British soldier was killed in Helmand Province.


American and Afghan officials have been struggling to figure out how large a factor Taliban infiltration or coercion has been in such attacks. Although insurgent contact has been clear in some cases, many of the attacks have seemed to come out of personal animosity or outrage, attributed to culture clash or growing Afghan anger at what they see as an unwelcome occupation by the United States and its allies.


“The loss of any team member is tragic, but to have this happen over the holidays makes it seem all the more unfair,” Steven F. Gaffney, the chairman of DynCorp, said in a statement.


The company also released a statement attributed to the victim’s wife, Rennae Griffin. “My husband was a thoughtful, kind, generous and loving man who was selfless in all his actions and deeds,” it said.


In other violence on Monday, a coalition member was killed in an insurgent attack in eastern Afghanistan, and an Afghan Local Police commander killed five fellow officers at a checkpoint in Jowzjan Province in the north. Dur Mohammad, the commander at the checkpoint, shot and killed five officers under his command, according to Gen. Abdul Aziz Ghairat, the provincial police chief. He said the commander fled after the shooting. General Ghairat did not offer a motive, but said that Mr. Mohammad had connections with the Taliban in the area.


The Afghan Local Police program, which seeks to bring armed elements — including some former insurgents — into government service, has drawn criticism because of a series of episodes in which the armed elements have switched allegiances, sometimes repeatedly.


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Fifth-gen iPad reportedly due in March along with Retina iPad mini







Rumors that a second-generation iPad mini with a Retina display is set to launch ahead of Apple’s typical annual schedule next year have been swirling, and now it appears Apple’s (AAPL) full-size iPad may be sticking to its new semiannual release schedule. According to a report from Japanese blog Makotakra that cites an anonymous “inside source,” Apple plans to launch a new thinner, lighter 9.7-inch iPad as soon as March 2013. The fourth iPad model was just released last month alongside the iPad mini, but March was also suggested in recent Retina iPad mini rumors. Makotakra states that the new iPad will adopt styling queues from the current iPad mini model, unifying the look of Apple’s larger tablet with the iPad mini and iPhone 5.


[More from BGR: First photos of BlackBerry 10 ‘N-Series’ QWERTY smartphone leak]






This article was originally published by BGR


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Pagano back to coach Colts after cancer treatment


INDIANAPOLIS (AP) — Chuck Pagano was so eager to get back to work Monday, he was the first one to show up at team headquarters.


Long before meeting with his players, the Colts first-year coach drove quietly into the complex, walked into the office where the lights have remained on for nearly three months and began preparing for Sunday's game against AFC South champion Houston like it was another at the day office.


Hardly. It was the biggest milestone yet in an incredibly emotional season in which Pagano has beaten leukemia and the Colts have been a most pleasant surprise in reaching the playoffs under interim coach Bruce Arians.


"I asked him if he would ... take over the reins and what a masterful, masterful job you did Bruce," Pagano said with Arians nearby at the news conference. "You carried the torch and all you went out and did was win ballgames, you got our 10th win yesterday and you got us into the playoffs and you did it with dignity and you did it with class. I can't thank you enough."


Players, coaches and staff members had been anticipating this day from the moment they learned Pagano was taking an indefinite leave to fight cancer, Oct. 1.


So when the 52-year-old first-time head coach returned, the 24-hour rule was cast aside — giving the Colts (10-5) another 24 hours to celebrate something far more important than reaching the playoffs.


"I know Chuck is ready for this challenge," said Colts owner Jim Irsay. " I know the time is right for him to grab the reins and get the head coaching cap on and begin the journey.


"The great thing about the National Football League is that so much attention gets paid to it, so many other things happen beside win and losses and the inspiration Chuck has shown to others and the time Chuck has spent connecting with others, it really is miraculous. It's a fairytale story, its' a Hollywood script, it's all of those things."


When Pagano arrived, he drove past an inflatable Colts player with the words "Welcome Back Chuck" printed on its chest. Normally, that spot is reserved for a message for the Colts to beat their next opponent.


When he spoke at a private team meeting, cheering could be heard in the media room.


If all goes well at practice this week, Pagano will be back on the sideline for the first time since Jacksonville scored a last-minute touchdown on an 80-yard TD pass in Week 3, handing Indy it's only home loss this season.


Pagano began the first of three rounds of chemotherapy Sept. 26, after the team completed its final practice during a bye week.


Arians, a prostate cancer survivor, immediately established the goal: Play long enough so Pagano could return to the sideline this season.


Indianapolis did better than anyone could have expected under Arians, who had spent two decades as an NFL assistant but had never been in charge of an NFL team. The Colts went 9-4 under Arians, who tied the league record for wins after a midseason coaching change, joined the 2008 Miami Dolphins as the only teams in league history to lose 14 or more games one season and win 10 or more the next and became the fourth team in league history to win only two games one season and 10 or more the next.


___


Online: http://pro32.ap.org/poll and http://twitter.com/AP_NFL


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Books: From Bang to Whimper: A Heart Drug’s Story





On June 23, 2005, American medicine managed to take a small step forward and a giant step backward at precisely the same time, with government approval of the first medication to be earmarked for a specific racial group. It was BiDil, a drug designed to treat heart failure in blacks.




Enthusiasts hailed BiDil’s approval by the Food and Drug Administration as a landmark event in the nascent field of pharmacogenomics, which aims to create drugs tailored to fit an individual’s genetic makeup as precisely as a bespoke suit drapes its owner’s shoulders. Critics just winced and clocked one more misstep in medicine’s long history of race-related disasters.


You would think that the elucidation of the human genome would have cleared up most of the hoary untruths surrounding race and health. But as Jonathan Kahn makes clear in his worthy if convoluted review of the events surrounding the birth of BiDil, the genome has in many respects only made things worse.


It has been clear for decades that race has minimal relevance to the body’s inner workings. Research has repeatedly shown that the biologic variations among individuals of the same race are reliably great enough for race to retain little utility as a biologic predictor. You might as well sort people by height. Or, in the words of an editorial writer for Nature Biotechnology in 2005, “Pooling people in race silos is akin to zoologists grouping raccoons, tigers and okapis on the basis that they are all stripy.”


But old misconceptions die hard, particularly for entrepreneurs eagerly awaiting cash bonanzas from the genomic revolution.


Race may be irrelevant; it may be, as Dr. Francis Collins, the director of the National Institutes of Health, put it, “a weak and imperfect proxy” for genetic differences. But it is also a familiar concept — and asking people what race they are is substantially cheaper than genotyping them.


So in a peculiar paradox, race has come to serve in some circles as a crude surrogate for genetic analysis until actual genomic medicine comes along — a temporary bridge from now to later, known to be flawed but still a quasi-legitimate stand-in for the real thing.


Against this background unfolds the story of BiDil, a drama of greed and good intentions.


Several observations prompted the drug’s development. Among them was the common assertion from the last century that blacks with heart failure were more likely to die than whites. (Mr. Kahn does an impressive job of researching and debunking this statistic.) Then there was the belief that blacks often reacted badly to some of the newer drugs used for treating heart failure, and the results of a study dating from the 1980s suggesting that many black patients did well with two old standby drugs.


Those two drugs were (and are) on sale as generics, costing pennies a pill. But just suppose they were combined into a single pill that could be then specifically marketed to patients who just happened to be thought in particular need of effective medication? Now there was a pharmacologic and marketing plan that would extend a lucrative new patent for decades.


And so it came to pass that a collection of eager investors and some of the nation’s foremost cardiologists smiled on the results of an industry-sponsored trial performed on self-identified black subjects with heart failure: The two cheap drugs combined into the not-so-cheap BiDil reduced mortality by 40 percent compared with placebo. This figure was impressive enough to end the trial early and speed BiDil to market.


How did whites do on BiDil? Nobody bothered to check.


Mr. Kahn deserves credit for teasing out all the daunting complexities behind these events, including the details of genetic analysis, the perils of racial determinations and the minutiae of patent law. Unfortunately, though, he suffocates his powerful subject in a dry, repetitive, ponderous read.


A law professor with a doctorate in history and longstanding interest in race issues, Mr. Kahn trudges a partisan path through the drama in which he himself was a player. (He testified before an F.D.A. advisory committee that BiDil should be approved without racial qualifications.)


He heads bravely into many statistical thickets, but omits relevant clinical data; he repeatedly refers to the trial that led to BiDil’s approval, for instance, but I could find its numerical findings nowhere in the book and had to look them up. In a story that fairly drips with potential human interest, he offers the reader not one sip.


The issues raised on every page are so important and so thought-provoking that it would be irresponsible to warn interested readers away. Still, it would be almost as irresponsible to misrepresent the difficulty of the journey.


As it happens, BiDil itself has had a remarkably inglorious career. Despite its much-trumpeted release, patients did not request the medication, and practicing doctors did not prescribe it.


NitroMed, the company that developed it, sponsored no further studies and failed in 2009.


The drug still lingers on the market; Mr. Kahn writes that BiDil may be resurrected in sustained-release form — that other time-honored technique for wringing a few more years from a drug’s patent.


For a parable of early 21st-century medicine, as it treads water between past and future and never hesitates to reach for a buck, it doesn’t get much better than BiDil.


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Syrian Airstrikes Reportedly Kill Dozens at Bakery





BEIRUT, Lebanon — A Syrian warplane was reported to have conducted airstrikes that killed dozens of people lined up for bread at a bakery in the central town of Hilfaya, according to antigovernment activists in the area.




The attack, and its toll, could not immediately be confirmed. Samer, a local activist in the town, said he ran to the bakery soon after he heard a warplane, followed by bomb explosions and finally the sound of ambulances. “There were bodies everywhere,” he said, adding that he saw tens of bodies taken away in cars.


Photographs he said he took at the bakery showed bodies in a heap on a bloody sidewalk outside a low-slung building that was blackened with soot and stained with patches of blood, high on the walls. Amateur video showing what activists said was the aftermath of the attack showed roughly a dozen people lying on the ground, some wounded and several apparently dead.


In one of Samer’s photograph, a man stared in shock at the scene, with his hands resting on his head, while another carried body parts. Bystanders searched for survivors under rubble from the building. Another man picked up a piece of bread, lying next to someone’s slippers.


The reason for the attack was unclear, but activists said that rebel fighters occupied Hilfaya last week as part of a broader offensive to seize territory around the city of Hama, where the government has kept tight control after suppressing protests in the city last year.


Civilians have been caught between the two sides. On Friday, rebel fighters posted a video threatening to attack Christian villages with artillery while asserting that the residents were shielding government loyalists. In the last few days, Hilfaya has come under repeated shelling from loyalist positions in a neighboring village, activists said.


The bakery was one of three in the city. When word spread on Sunday that a flour shipment from Turkey had come in, people began lining up around noon, waiting for their turn at its windows for bread after a stretch of days when the bakeries had been idled. At least three bombs fell near the bakery, Samer and other activists said.


The attack came as the international envoy to Syria, Lakhdar Brahimi, arrived in the capital, Damascus, where he was expected to meet with President Bashar al-Assad. His visit had been rumored but not previously announced, signaling concerns about security as the fighting between opposition fighters and the government intensified in the capital.


Mr. Brahimi made no public comment on Sunday, and the Syrian information minister said during a news conference that he had no knowledge of the envoy’s visit. Mr. Brahimi traveled by land from Beirut because of fighting between the rebels and government forces near the Damascus airport, Lebanese airport officials told The Associated Press.


His visit was likely to add fuel to the speculation about a deal to remove Mr. Assad from power. Rebel forces have claimed gains near government strongholds, and international aid agencies are warning of a growing humanitarian crisis in the winter months.


Russia, one of Syria’s most reliable allies, has recently sent signals that it is distancing itself from the Syrian president. On Saturday, the Russian foreign minister, Sergey V. Lavrov, said several countries in the region had offered Mr. Assad asylum, while adding that Moscow was not willing to mediate on their behalf.


Ellen Barry contributed reporting from Moscow; Hala Droubi from Jidda, Saudi Arabia; and Hwaida Saad from Beirut.



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